Natural Selection Shapes Codon Usage in the Human Genome
Ryan S. Dhindsa, Brett Copeland, Anthony M. Mustoe, David B. Goldstein
Topics & Concepts
Codon usage biasBiologySynonymous substitutionGeneticsTranslational efficiencyNatural selectionGeneGenomeSilent mutationHuman genomeMutationAlternative splicingSelection (genetic algorithm)Computational biologyTranslation (biology)Messenger RNAComputer scienceMissense mutationArtificial intelligenceRNA and protein synthesis mechanismsRNA modifications and cancerRNA Research and Splicing