Quantitative polarimetry Mueller matrix decomposition approach for diagnosing melanoma and non-melanoma human skin cancer
Armaghan Vahidnia, Khosro Madanipour, Robabeh Abedini, Reza Karimi, Joseph Sanderson, Zahra Zare, Parviz Parvin
Abstract
A simple and effective polarimetric technique is used to discriminate benign lesions from cancerous ones. This method is based on key polarimetric parameters of diattenuation, depolarization, and retardance. Several samples of human skin exhibiting three kinds of cancer as well as benign specimens are examined using a polarimetric technique and results are compared with pathology diagnosis. In this study polarimetric parameters are taken into account as a reliable diagnostic tool to distinguish the cancerous lesions precisely and non-invasively.
Topics & Concepts
PolarimetryMueller calculusMelanomaCancerScanning laser polarimetryMatrix (chemical analysis)Skin cancerDiagnostic accuracyMedicinePathologyRadiologyOpticsMaterials sciencePhysicsInternal medicineCancer researchOptical coherence tomographyComposite materialNerve fiber layerScatteringOptical Polarization and EllipsometrySpectroscopy and Chemometric AnalysesSpectroscopy Techniques in Biomedical and Chemical Research