Electrochemical C–H Sulfonylation of Hydrazones
Biswajit Sarkar, Payel Ghosh, Alakananda Hajra
Abstract
We have developed an electrochemical method for the direct C–H sulfonylation of aldehyde hydrazones using sodium sufinates as the sulfonylating agent under supporting electrolyte-free conditions. This straightforward sulfonylation strategy afforded a library of ( E )-sufonylated hydrazones with high tolerance of various functional groups. The radical pathway of this reaction has been revealed by the mechanistic studies.
Topics & Concepts
ChemistryElectrochemistryCombinatorial chemistryOrganic chemistryElectrodePhysical chemistrySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods