Cellular membrane-targeting ruthenium complexes as efficient photosensitizers for broad-spectrum antibacterial activity
Yi Wang, Yatao Hu, Hailin Zhang, Yuyu Chen, Hongdong Shi, Jin‐Gang Liu, Qianling Zhang
Abstract
; these values are lower than those of streptomycin and methicillin. This work combined the merits of cell membrane targeting and photodynamic therapy for antibacterial activity. The findings might open up a new avenue for effective anti-infection treatment and other medical applications.
Topics & Concepts
RutheniumPhotosensitizerAntibacterial activityChemistryEscherichia coliBroad spectrumMembraneIntracellularPhotodynamic therapyMinimum inhibitory concentrationAmine gas treatingCombinatorial chemistryStaphylococcus aureusBacteriaPhotochemistryBiophysicsAntimicrobialBiochemistryOrganic chemistryBiologyCatalysisGeneticsGeneMetal complexes synthesis and propertiesAdvanced biosensing and bioanalysis techniquesAdvanced Nanomaterials in Catalysis