Polystyrene microplastic-induced oxidative stress triggers intestinal barrier dysfunction via the NF-κB/NLRP3/IL-1β/MCLK pathway
Guodong Zeng, Jingyi Li, Yuanli Wang, Jingran Su, Zhongbing Lu, Fang Zhang, Wenjun Ding
Topics & Concepts
Oxidative stressMyosin light-chain kinaseDownregulation and upregulationChemistryTight junctionInflammasomeReactive oxygen speciesNF-κBIntestinal permeabilityTumor necrosis factor alphaIκB kinaseCell biologyBiochemistryBiologySignal transductionImmunologyMyosinReceptorGeneHeavy Metal Exposure and ToxicityWound Healing and TreatmentsOral microbiology and periodontitis research