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Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA binding

Dilep Kumar Sigalapalli, Gaddam Kiranmai, G. Parimala Devi, Ramya Tokala, Sravani Sana, Chaturvedula Tripura, Govinda Shivaji Jadhav, Manasa Kadagathur, Nagula Shankaraiah, Narayana Nagesh, Bathini Nagendra Babu, Neelima D. Tangellamudi

2021Bioorganic & Medicinal Chemistry27 citationsDOI

Topics & Concepts

ChemistryAnnexinA549 cellTubulinCell cycleApoptosisIC50In vitroPyridineMicrotubule polymerizationCytotoxicityCancer cellCell cultureStereochemistryBiochemistryMicrotubuleMolecular biologyCancerCell biologyBiologyOrganic chemistryGeneticsSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsClick Chemistry and Applications
Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA binding | Litcius