Gly-Pro-Val-Gly-Pro-Ser Peptide Fish Collagen Improves Skin Moisture and Wrinkles with Ameliorated the Oxidative Stress and Pro-inflammatory Factors in Skin Photoaging Mimic Models
Wonhee Cho, Jeongjin Park, Minhee Lee, Seong-Hoo Park, Jaeeun Jung, Jinhak Kim, Sangwon Eun, Jinkyung Kim
Abstract
, FC down-regulated the protein expression of the c-Jun N-terminal kinase, c-Fos, c-Jun, and MMP pathways and up-reg-ulated that of the transforming growth factor-β receptor I, collagen type I, procollagen type I, and small mothers against decapentaplegic homolog pathways. Our results suggest that FC can be effective against UV-B induced skin photoaging by improving skin dryness and wrinkle formation through antioxidant and anti-inflammatory properties.
Topics & Concepts
PhotoagingChemistryHyaluronic acidCeramideOxidative stressSkin AgingIn vivoSphingolipidAntioxidantHuman skinBiochemistryBiologyApoptosisMedicineAnatomyDermatologyGeneticsBiotechnologySkin Protection and AgingOlfactory and Sensory Function Studiesmelanin and skin pigmentation