Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma
Catherine S. Grasso, Jennifer Tsoi, Mykola Onyshchenko, Gabriel Abril-Rodríguez, Petra Ross‐Macdonald, Megan Wind‐Rotolo, Ameya S. Champhekar, Egmidio Medina, Davis Y. Torrejon, Daniel Sanghoon Shin, Phuong Tran, Yeon Joo Kim, Cristina Puig-Saus, Katie M. Campbell, Agustin Vega-Crespo, Michael J. Quist, Christophe Martignier, Jason J. Luke, Jedd D. Wolchok, Douglas B. Johnson, Bartosz Chmielowski, F. Stephen Hodi, Shailender Bhatia, William H. Sharfman, Walter J. Urba, Craig L. Slingluff, Adi Diab, John B.A.G. Haanen, Salvador Martín‐Algarra, Drew M. Pardoll, Valsamo Anagnostou, Suzanne L. Topalian, Victor E. Velculescu, Daniel E. Speiser, Anusha Kalbasi, Antoni Ribas
Topics & Concepts
IpilimumabTranscriptomeImmune checkpointNivolumabMelanomaCancer researchImmune systemBlockadeBiologySignal transductionWnt signaling pathwayInterferonImmunologyImmunotherapyT cellReceptorCell biologyGeneticsGeneGene expressionCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCAR-T cell therapy research