Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions
Maria Yanez, Tamara Marín, Elisa Balboa, Andrés D. Klein, Alejandra Álvarez, Silvana Zanlungo
Topics & Concepts
NPC1EndosomeEndocytic cycleLysosomal storage diseaseNiemann–Pick diseaseBiologyNeurodegenerationLysosomeSphingolipidCell biologyNiemann–Pick disease, type CNeuroscienceEndocytosisGeneticsBiochemistryEnzymeDiseaseCellMedicineIntracellularCholesterolPathologyLysosomal Storage Disorders ResearchCalcium signaling and nucleotide metabolismFamily and Disability Support Research