Pan-Genome Analysis of Campylobacter: Insights on the Genomic Diversity and Virulence Profile
Chaofang Zhong, Bingpeng Qu, Gang Hu, Kang Ning
Abstract
Pathogenic members of the genus Campylobacter are recognized as one of the major causative agents of human bacterial gastroenteritis. This study revealed the pan-genome of 39 Campylobacter species, provided the most updated reconstruction of the global virulence gene pool of 39 Campylobacter species, and identified species-related virulence differences. This study highlighted the basic conserved functionality and specificity of pathogenicity that are crucial to infection, which was critical for improving the diagnosis and prevention of Campylobacter infections.
Topics & Concepts
VirulenceCampylobacterBiologyGenomeGeneticsGeneCampylobacter jejuniMicrobiologyBacteriaSalmonella and Campylobacter epidemiologyViral gastroenteritis research and epidemiologyLeptospirosis research and findings