Silk-Based 3D Porous Scaffolds for Tissue Engineering
Menglin Xiao, Jinrong Yao, Zhengzhong Shao, Xin Chen
Abstract
silkworm, stands out as a biomaterial due to its nontoxic nature, excellent biocompatibility, and adjustable biodegradability. Porous scaffolds, a type of biomaterial, are crucial for creating an optimal microenvironment that supports cell adhesion and proliferation, thereby playing an essential role in tissue remodeling and repair. Therefore, this review focuses on 3D porous silk fibroin-based scaffolds, first summarizing their preparation methods and then detailing their regenerative effects on bone, cartilage, tendon, vascular, neural, skin, hepatic, and tracheal epithelial tissue engineering in recent years.
Topics & Concepts
FibroinSILKTissue engineeringMaterials sciencePorosityPolymer scienceScaffoldNanotechnologyBiomedical engineeringComposite materialEngineeringSilk-based biomaterials and applicationsElectrospun Nanofibers in Biomedical ApplicationsBone Tissue Engineering Materials