E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones
Tasuku Ishida, Alessio Ciulli
Topics & Concepts
Ubiquitin ligaseDNA ligaseUbiquitinDrug discoveryComputational biologyCereblonProtein degradationUbiquitin-Protein LigasesProteasomeChemistryBiologyBiochemistryDNAGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments