Antibiotics and Innate Immunity: A Cooperative Effort Towards the Successful Treatment of Infections
Andrew D. Berti, Warren E. Rose, Victor Nizet, George Sakoulas
Abstract
Despite the common ancestry of antimicrobial and immunological science, a divergence driven by artificially construed paradigms in microbiology has placed limits on how we understand the mechanisms of antibiotics in vivo. We summarize recent updates on data that shed light on how antibiotics interact with components of innate immunity.
Topics & Concepts
Innate immune systemAntibioticsImmunityMedicineAntimicrobialImmunologyMicrobiologyComputational biologyBiologyImmune systemEscherichia coli research studiesImmune Response and InflammationClostridium difficile and Clostridium perfringens research