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Chemical characterization, antioxidant, antibacterial and enzyme inhibitory properties of Canthium coromandelicum, a valuable source for bioactive compounds

Singamoorthy Amalraj, Jayaraj Krupa, Venkatraman Sriramavaratharajan, Veemarasu Mariyammal, Ramar Murugan, Muniappan Ayyanar

2020Journal of Pharmaceutical and Biomedical Analysis41 citationsDOIOpen Access PDF

Abstract

of 30.82 μg/mL) respectively.Methanolic and hydroalcoholic extracts at 750 μg/mL showed maximum antibacterial activity against S. typhi and S. flexneri respectively. Also, significant correlation was found between V. cholerae and R. equi as well as V. cholerae and S. epidermis. To conclude, C. coromandelicum could be considered as a natural antioxidant and potential source for therapeutic applications. However, widespread study is necessary to screen the role of recorded phytochemicals through in vivo studies to support its use in traditional medicine.

Topics & Concepts

ChemistryAntioxidantDPPHSqualeneAntibacterial activityIC50Linoleic acidTraditional medicineBiochemistryBacteriaIn vitroFatty acidBiologyMedicineGeneticsPhytochemistry and Biological ActivitiesPhytochemicals and Antioxidant ActivitiesEssential Oils and Antimicrobial Activity