A 28-day clinical trial of aerosolized hyaluronan in alpha-1 antiprotease deficiency COPD using desmosine as a surrogate marker for drug efficacy
Jerome Cantor, Shuren Ma, Xingjian Liu, Michael Campos, Charlton Strange, James Stocks, Megan Devine, Sherif G El Bayadi, Randolph J. Lipchik, Robert A. Sandhaus, Gerard M. Turino
Topics & Concepts
MedicineSputumCOPDDesmosinePlaceboInhalationGastroenterologyUrineInternal medicineSurrogate endpointRandomized controlled trialClinical trialElastinAnesthesiaPathologyTuberculosisAlternative medicineProteoglycans and glycosaminoglycans researchInhalation and Respiratory Drug DeliveryConnective tissue disorders research