Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways
Bence Hegyi, Johanna M. Borst, Logan R.J. Bailey, Erin Y. Shen, Austen J. Lucena, Manuel F. Navedo, Julie Bossuyt, Donald M. Bers
Topics & Concepts
Internal medicineEndocrinologyNADPH oxidaseDownregulation and upregulationProtein kinase CChemistryDiabetes mellitusRepolarizationPotassium channelInward-rectifier potassium ion channelSignal transductionMedicineReceptorOxidative stressBiochemistryIon channelElectrophysiologyGeneCardiac electrophysiology and arrhythmiasIon channel regulation and functionCardiovascular Function and Risk Factors