Rational design of a nitroreductase-activatable two-photon fluorescent probe for hypoxia imaging in cell and in vivo
Yue Wang, Li Zhang, Yan Huang, Xiaoyan Wang, Liangwei Zhang, Lingxin Chen
Topics & Concepts
NitroreductaseIn vivoHypoxia (environmental)Cancer researchChemistryA549 cellGemcitabineTumor hypoxiaCarboplatinPharmacologyChemotherapyMedicineIn vitroCisplatinEnzymeBiologyOxygenBiochemistryInternal medicineRadiation therapyBiotechnologyOrganic chemistryCancer, Hypoxia, and MetabolismNanoplatforms for cancer theranosticsPhotodynamic Therapy Research Studies