Characterization of Newly Detected Costal Pleura–attached Noncalcified Nodules at Annual Low-Dose CT Screenings
Yeqing Zhu, Rowena Yip, Nan You, Qiang Cai, Claudia I. Henschke, David F. Yankelevitz, for the International Early Lung Cancer Action Program Investigators, Claudia I. Henschke, David F. Yankelevitz, Rowena Yip, Dongming Xu, Mary Salvatore, Raja M. Flores, Andrea Wolf, David S. Mendelson, Dorothy I. McCauley, Mildred Chen, Daniel M. Libby, Olli S. Miettinen, James P. Smith, Mark Pasmantier, Anthony P. Reeves, Steven Markowitz, Albert Miller, José Cervera Deval, Heidi Roberts, Demetris Patsios, Shusuke Sone, Takaomi Hanaoka, Javier J. Zulueta, Luis M. Montuenga, María D. Lozano, Ralph W. Aye, Thomas W. Bauer, Stefano Canitano, Salvatore Giunta, Enser Cole, Karl Klingler, John H. M. Austin, Gregory D. Pearson, Dorith Shaham, Cheryl Aylesworth, Patrick Meyers, Shahriyour Andaz, Davood Vafai, David P. Naidich, Georgeann McGuinness, Barry Sheppard, Matthew D. Rifkin, M. Kristin Thorsen, Richard M. Hansen, Samuel Kopel, William Mayfield, Dan W. Luedke, Donald Klippenstein, Alan Litwin, Peter Loud, Leslie J. Kohman, Ernest M. Scalzetti, Richard J. Thurer, Arfa Khan, Rakesh Shah, Xueguo Liu, Gary Herzog, Diane Yeh, Ning Wu, J. Lowry, Mary Salvatore, Carmine Frumiento, Michael V. Smith, Robert J. Korst, Jana Taylor, Robert T. Heelan, Michelle S. Ginsberg, Michaela Straznicka, Mark Widmann, G Cecchi, Terence A.S. Matalon, Paul Scheinberg, Shari-Lynn Odzer, David R. Olsen, Fred Grannis, Arnold Rotter, Daniel Ray, David Mullen, Peter H. Wiernik, Edson H. Cheung, Melissa Lim, Louis DeCunzo, Robert Glassberg, Harvey I. Pass, Carmen Endress, Mark Yoder, Palmi Shah, Laura S. Welch, Michael Kalafer, Jeremy Green, James Walsh, David Bertsch, Elmer Camacho
Abstract
= .045) within a 10.0 mm radius. All 22 solid CP-NCNs less than 10.0 mm in average diameter with triangular or LOS shapes and smooth margins were benign, and none of the 21 solid malignant CP-NCNs had these characteristics. Intra- and interobserver agreement for triangular or LOS-shaped CP-NCNs with smooth margins was almost perfect (0.77 and 0.69, respectively). Conclusion The same follow-up recommendation developed for baseline costal pleura-attached noncalcified nodules (CP-NCNs) can be used for CP-NCNs newly identified at annual screening rounds. © RSNA, 2021.