An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo
Binsheng Wang, Lichao Wang, Nathan Gasek, Yueying Zhou, Taewan Kim, Chun Guo, Evan R. Jellison, Laura Haynes, Sumit Yadav, Tamar Tchkonia, George A. Kuchel, James L. Kirkland, Ming Xu
Topics & Concepts
Genetically modified mouseTransgeneIn vivoCell biologyBiologyPopulationCellMolecular biologyGeneMedicineGeneticsEnvironmental healthTelomeres, Telomerase, and SenescenceImmune cells in cancerMicroRNA in disease regulation