Plant and fungal products that extend lifespan in Caenorhabditis elegans
Jan Martel, Cheng-Yeu Wu, Hsin‐Hsin Peng, Yun-Fei Ko, Hung-Chi Yang, John Ding‐E Young, David M. Ojcius
Abstract
Plant and fungal products that extend lifespan in Caenorhabditis elegans – INTERVENTIONS TO DELAY AGING Aging can be modulated by genes and lifestyle. For instance, specific gene variants of insulin-like growth factor-1 (IGF-1) receptor and forkhead box O3A (FOXO3A) are associated with longer lifespan in centenarians [1]. In terms of lifestyle, one of the most studied interventions that delay aging is caloric restriction (CR), which can increase (...)
Topics & Concepts
Caenorhabditis elegansBiologyBiogenesisHormesisAutophagyCaenorhabditisLongevityModel organismCell biologyMechanism (biology)GeneticsGeneBiochemistryOxidative stressPhilosophyApoptosisEpistemologyGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninGenomics, phytochemicals, and oxidative stress