Pig models for Duchenne muscular dystrophy – from disease mechanisms to validation of new diagnostic and therapeutic concepts
Michael Stirm, Lina Marie Fonteyne, Bachuki Shashikadze, Jan B. Stöckl, Mayuko Kurome, Barbara Keßler, Valeri Zakhartchenko, Elisabeth Kemter, Helmut Blum, Georg J. Arnold, Kaspar Matiasek, Rüdiger Wanke, Wolfgang Wurst, Hiroshi Nagashima, Ferdinand Knieling, Maggie C. Walter, Christian Kupatt, Thomas Fröhlich, Nikolai Klymiuk, Andreas Blutke, Eckhard Wolf
Topics & Concepts
Duchenne muscular dystrophyDystrophinGenome editingCRISPRMedicineDiseaseExon skippingBioinformaticsMuscular dystrophySomatic cellPathologyBiologyExonGeneGeneticsInternal medicineAlternative splicingMuscle Physiology and DisordersTissue Engineering and Regenerative MedicineVirus-based gene therapy research