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Electrochemical Oxidation of Methane to Methylamine

Qiang Song, Wanping Xu, Xin Zeng, Tianqi Zhang, Jungmi Hong, Patrick J. Cullen

2025Journal of the American Chemical Society9 citationsDOI

Abstract

The electrochemical methane (CH 4 ) oxidation reaction under ambient conditions is a promising approach for natural gas utilization. However, the highly stable nature of CH 4 restrains efficient cleavage of the C–H bond without overoxidation. To this end, we proposed a coupled oxidative strategy for converting CH 4 to value-added products via NH 2 intermediates. The ammonia-oxidation-driven anodic reaction facilitates the formation of NH 2 species and activates CH 4 through nucleophilic attack to achieve C–N bond formation. Further the generated methylamine could be protected from overoxidation in the ammonia-based anolyte. Under such conditions, a methylamine productivity of 3.8 mmol g –1 cat h –1 at 1.55 V vs a reversible hydrogen electrode is reported. This work provides new insights into electrocatalytic C–N coupling based on the ammonia oxidation reaction, which could extend to other alkane or alkene conversions.

Topics & Concepts

ChemistryMethylamineElectrochemistryMethaneEnvironmental chemistryInorganic chemistryOrganic chemistryElectrodePhysical chemistryCatalysis and Oxidation ReactionsCO2 Reduction Techniques and CatalystsCatalytic Processes in Materials Science
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