ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase
Xingyu Zhang, Li Tang, Zhentao Zhang
Topics & Concepts
ADAM10DisintegrinMetalloproteinaseAlpha secretaseChemistryCell biologyAmyloid precursor protein secretaseAmyloid precursor proteinTransmembrane domainMatrix metalloproteinaseFurinTransmembrane proteinBiochemistryAlzheimer's diseaseEnzymeBiologyReceptorInternal medicineMedicineDiseasePeptidase Inhibition and AnalysisProtease and Inhibitor MechanismsSignaling Pathways in Disease