Electro-organic synthesis of C-5 sulfenylated amino uracils: Optimization and exploring topoisomerase-I based anti-cancer profile
Payal Rani, Sandhya Chahal, Roshan Kumar, Mayank Mayank, Prof Parvin Kumar, Arvind Negi, Rajvir Singh, Sudhir Kumar, Ramesh Kataria, Gaurav Joshi, Jayant Sindhu
Topics & Concepts
ChemistryTopoisomeraseContext (archaeology)In silicoIntercalation (chemistry)PyrimidineCancer cellDNABiochemistryCancerIC50Combinatorial chemistryStereochemistryIn vitroBiologyGeneticsOrganic chemistryPaleontologyGeneCancer therapeutics and mechanismsSynthesis and biological activitySynthesis and Biological Evaluation