Metformin-induced TTP mediates communication between Kupffer cells and hepatocytes to alleviate hepatic steatosis by regulating lipophagy and necroptosis
Jeong-Min Park, So‐Young Rah, Hyeong Seok An, Jong Youl Lee, Gu Seob Roh, Stefan W. Ryter, Jeong Woo Park, Chae Ha Yang, Young‐Joon Surh, Uh‐Hyun Kim, Hun‐Taeg Chung, Yeonsoo Joe
Topics & Concepts
SteatosisNecroptosisMetforminHepatocyteFatty liverAMPKInternal medicineCancer researchSteatohepatitisEndocrinologyTFEBChemistryProgrammed cell deathCell biologyBiologyMedicineApoptosisAutophagyProtein kinase AKinaseDiabetes mellitusBiochemistryDiseaseIn vitroLiver Disease Diagnosis and TreatmentLiver physiology and pathologyMetabolism, Diabetes, and Cancer