Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015
Jae Hoon Woo, Young Eui Jeong, Jung Eun Jo, Sang‐Mu Shim, Jungsang Ryou, Kyung-Chang Kim, Won Ja Lee, Joo-Yeon Lee
Abstract
J apanese encephalitis is caused by Japanese enceph- alitis virus (JEV), a mosquitoborne virus of the family Flaviviridae, genus Flavivirus (1). The JEV genome is composed of a single-stranded, positive-sense RNA of 11 kb with a single open reading frame (ORF) encoding a polyprotein. The polyprotein is processed into 3 structural proteins, capsid, membrane, and envelope (E), and 7 nonstructural proteins, NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5 (2).
Topics & Concepts
GenotypeVirologyEncephalitisJapanese encephalitisVirusBiologyMedicineGeneticsGeneMosquito-borne diseases and controlViral Infections and VectorsVector-borne infectious diseases