Enhancing the binding of the β-sheet breaker peptide LPFFD to the amyloid-β fibrils by aromatic modifications: A molecular dynamics simulation study
Pavan Krishna Kanchi, Ashok Kumar Dasmahapatra
Topics & Concepts
FibrilPeptideChemistryBeta sheetAmino acidAromatic amino acidsBiophysicsAmyloid (mycology)Amyloid fibrilBiochemistryAmyloid βBiologyDiseasePathologyMedicineInorganic chemistryAlzheimer's disease research and treatmentsSupramolecular Self-Assembly in MaterialsProtein Structure and Dynamics