Synthesis of 3-<i>O</i>-Acetyl-11-keto-β-boswellic Acid (AKBA)-Derived Amides and Their Mitochondria-Targeted Antitumor Activities
Changhao Li, Qiaobian He, Yuwen Xu, Hong‐Xiang Lou, Peihong Fan
Abstract
represented a compound with improved antiproliferative effects for cancer therapy working through new mechanisms.
Topics & Concepts
Mitochondrial permeability transition poreVacuolizationChemistryApoptosisReactive oxygen speciesMitochondrionProgrammed cell deathMoietyCell cycle checkpointStereochemistryBiochemistryCell cycleBiologyEndocrinologyPharmacological Effects of Medicinal PlantsDrug Transport and Resistance MechanismsBone Metabolism and Diseases