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Editorial: Diagnostics and detection of African swine fever virus

Chengjun Zhang, Shuai Li, Mengjia Zhang, Yongtao Li, Luis G. Giménez‐Lirola, Bin Li, Wentao Li

2023Frontiers in Veterinary Science10 citationsDOIOpen Access PDF

Abstract

African swine fever virus (ASFV) is a large, enveloped, double-stranded DNA virus that causes a contagious and lethal hemorrhagic disease. Since its first detected in the sub-Saharan Africa, were remains endemic, ASFV rapidly spread to numerous countries including Europe, Asia, and the Caribbean, causing substantial economic losses to the swine industry. Currently, in the absence of commercially available efficacious vaccine, the control of African swine fever (ASF) primarily relies on implementing strict biosecurity measures. One of the key measures is the early and accurate diagnosis of ASF. Therefore, the development of sensitive, rapid, and user-friendly detection methods is crucial. Despite the widespread use of commercialized quantitative real-time PCR (qPCR) and ELISA kits for ASFV detection, many clinical demands remain unmet. This Research Topic, focused on novel diagnostic technologies for detecting ASFV, with the aim of encouraging new ideas that can improve the prevention and control strategies for ASF. This Research Topic included 13 articles, three of which presented novel ELISA detection methods, three were focused on qPCR methods, two utilized the CRISPR-Cas12a detection system, one evaluated both ELISA and qPCR methods, one article was related to animal experiments, while two discussed sample collection, and one introduced a new sequencing method.

Topics & Concepts

VirologyAfrican swine fever virusVirusAfrican swine feverBiologyAnimal Disease Management and EpidemiologyVector-Borne Animal DiseasesViral Infections and Immunology Research