Reproducibility of the neurocardiovascular responses to common laboratory-based sympathoexcitatory stimuli in young adults
Gabrielle A. Dillon, Zachary S. Lichter, Lacy M. Alexander, Lauro C. Vianna, Jing Wang, Paul J. Fadel, Jody L. Greaney
Abstract
The magnitude of the increases in blood pressure and muscle sympathetic nerve activity in response to sympathoexcitatory stimuli such as static handgrip, postexercise ischemia, and the cold pressor test are commonly used to assess neurocardiovascular responsiveness. However, limited studies have comprehensively examined the reproducibility of these responses. We demonstrate that the reproducibility of the pressor response to these perturbations was very good within an individual, whereas the reproducibility of the MSNA response was less consistent.
Topics & Concepts
ReproducibilityIsometric exerciseMicroneurographyMedicineIntraclass correlationCold pressor testBlood pressureInternal medicineCardiologyAnesthesiaHeart rateChemistryBaroreflexChromatographyHeart Rate Variability and Autonomic ControlCardiovascular and exercise physiologyThermoregulation and physiological responses