Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis
Andrew S. Riching, Etienne Danis, Yuanbiao Zhao, Yingqiong Cao, Congwu Chi, Rushita A. Bagchi, Brianna J. Klein, Hongyan Xu, Tatiana G. Kutateladze, Timothy A. McKinsey, Peter M. Buttrick, Kunhua Song
Topics & Concepts
GATA4ReprogrammingDemethylaseMEF2CHistoneTranscription factorHistone H3Cell biologyChemistryCancer researchCardiac fibrosisTransforming growth factorBiologyGeneGeneticsFibrosisInternal medicineMedicineCongenital heart defects researchGenetics and Neurodevelopmental DisordersPluripotent Stem Cells Research