Hypoxia activates SUMO-1-HIF-1α signaling pathway to upregulate pro-inflammatory cytokines and permeability in human tonsil epithelial cells
Yan Lin, Ming-Jing Wang, Zhen Xiao, Zhiyan Jiang
Topics & Concepts
Downregulation and upregulationInflammationGene knockdownHypoxia (environmental)UbiquitinGene silencingCell biologyProinflammatory cytokineSignal transductionTumor necrosis factor alphaBiologyCancer researchImmunologyChemistryCell cultureBiochemistryOxygenGeneticsOrganic chemistryGeneObstructive Sleep Apnea ResearchChronic Obstructive Pulmonary Disease (COPD) ResearchEicosanoids and Hypertension Pharmacology