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Bispecific targeting of CD20 and CD19 increases polyfunctionality of chimeric antigen receptor T-cell products in B-cell malignancies

Joanna Zurko, Huiqing Xu, Katherine E. Chaney, Dina Schneider, Anikó Szabó, Parameswaran Hari, Bryon D. Johnson, Nirav N. Shah

2022Cytotherapy14 citationsDOI

Topics & Concepts

CD19Chimeric antigen receptorAntigenCD20T cellChemistryImmune systemB cellImmunologyCD8Cytotoxic T cellCancer researchMolecular biologyBiologyAntibodyIn vitroBiochemistryCAR-T cell therapy researchImmunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies Research
Bispecific targeting of CD20 and CD19 increases polyfunctionality of chimeric antigen receptor T-cell products in B-cell malignancies | Litcius