PRMT1 promotes extracellular matrix degradation and apoptosis of chondrocytes in temporomandibular joint osteoarthritis via the AKT/FOXO1 signaling pathway
Qinhao Shen, Yiwen Xiao, Bei Cheng, Zheyi Sun, Yu Hu, Hefeng Yang, Yingwei Luo
Topics & Concepts
ChondrocyteProtein kinase BExtracellular matrixGene knockdownPI3K/AKT/mTOR pathwayApoptosisFOXO1Signal transductionCell biologyOsteoarthritisLY294002Cancer researchChemistryCartilageBiologyMedicinePathologyBiochemistryAnatomyAlternative medicineCancer-related gene regulationPeptidase Inhibition and AnalysisPlatelet Disorders and Treatments