TRPM2 deficiency in mice protects against atherosclerosis by inhibiting TRPM2–CD36 inflammatory axis in macrophages
Pengyu Zong, Jianlin Feng, Zhichao Yue, Albert S. Yu, Jean Vacher, Evan R. Jellison, Barbara A. Miller, Yasuo Mori, Lixia Yue
Topics & Concepts
TRPM2CD36Oxidative stressInflammationPathologicalInfiltration (HVAC)MacrophageDiseaseMedicineFoam cellImmunologyPathologyBiologyInternal medicineReceptorTransient receptor potential channelIn vitroPhysicsThermodynamicsBiochemistryIon Channels and ReceptorsInflammasome and immune disordersCalcium signaling and nucleotide metabolism