Litcius/Paper detail

Mechanism for the activation of the anaplastic lymphoma kinase receptor

Andrey V. Reshetnyak, P. Rossi, Alexander Myasnikov, Munia F. Sowaileh, Jyotidarsini Mohanty, Amanda Nourse, Darcie J. Miller, Irit Lax, Joseph Schlessinger, Charalampos G. Kalodimos

2021Nature70 citationsDOIOpen Access PDF

Topics & Concepts

Anaplastic lymphoma kinaseReceptor tyrosine kinaseChemistryTyrosine kinaseCell biologySignal transductionLigand (biochemistry)Receptor Protein-Tyrosine KinasesBiophysicsTransmembrane proteinBiologyBiochemistryReceptorPleural effusionMalignant pleural effusionMedicineSurgeryNeuroblastoma Research and TreatmentsCancer therapeutics and mechanismsCell death mechanisms and regulation