New indolin-2-ones, possessing sunitinib scaffold as HDAC inhibitors and anti-cancer agents with potential VEGFR inhibition activity; design, synthesis and biological evaluation
Mozhdeh Yousefian, Maryam Hashemi, Vahid Eskandarpour, Afshin Zarghi, Farzin Hadizadeh, Razieh Ghodsi
Topics & Concepts
ChemistrySunitinibScaffoldVEGF receptorsCancerCombinatorial chemistryPharmacologyCancer researchInternal medicineBiologyBiomedical engineeringMedicineHistone Deacetylase Inhibitors ResearchClick Chemistry and ApplicationsSynthesis and biological activity