ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy
Suleixin Yang, Ka Hong Wong, Peng Hua, Chengwei He, Hua Yu, Dan Shao, Zhi Shi, Meiwan Chen
Topics & Concepts
ApoptosisPlasmidMaterials scienceCancer therapyCancer researchCancerReactive oxygen speciesVector (molecular biology)Cancer cellNanotechnologyCell biologyMedicineBiologyRecombinant DNAGeneBiochemistryInternal medicineEpigenetics and DNA MethylationFerroptosis and cancer prognosisRNA modifications and cancer