Non-genomic activation of the AKT-mTOR pathway by the mitochondrial stress response in thyroid cancer
Woo Kyung Lee, Sun‐Mi Park, Seul Gi Lee, Seonhyang Jeong, Gibbeum Lee, Dongryeol Ryu, Kristina Schoonjans, Johan Auwerx, Jandee Lee, Young Suk Jo
Topics & Concepts
mTORC1PI3K/AKT/mTOR pathwayBiologymTORC2Cancer researchProtein kinase BDownregulation and upregulationCell biologyTranscription factorP70-S6 Kinase 1Mechanistic target of rapamycinCellular stress responseSignal transductionGeneticsGeneFight-or-flight responseCancer, Hypoxia, and MetabolismATP Synthase and ATPases ResearchHormonal Regulation and Hypertension