Tetrachlorobenzoquinone exhibits immunotoxicity by inducing neutrophil extracellular traps through a mechanism involving ROS-JNK-NOX2 positive feedback loop
Xuying Lv, Zixuan Liu, Lei Xu, Erqun Song, Yang Song
Topics & Concepts
Reactive oxygen speciesKinasep38 mitogen-activated protein kinasesMAPK/ERK pathwayNeutrophil extracellular trapsNADPH oxidaseToxicityPentachlorophenolNeurotoxicityChemistryExtracellularPhosphorylationProtein kinase ACell biologyPharmacologyBiochemistryBiologyImmunologyInflammationOrganic chemistryEnvironmental chemistryNeutrophil, Myeloperoxidase and Oxidative MechanismsNitric Oxide and Endothelin EffectsImmune Response and Inflammation