Litcius/Paper detail

VRK-1 extends life span by activation of AMPK via phosphorylation

Sang‐Soon Park, Murat Artan, Seung Hyun Han, Hae‐Eun H. Park, Yoonji Jung, Ara B. Hwang, Won‐Sik Shin, Kyong‐Tai Kim, Seung‐Jae Lee

2020Science Advances30 citationsDOIOpen Access PDF

Abstract

A conserved protein kinase VRK-1 increases life span by activating a key energy sensor AMPK in the roundworm C. elegans .

Topics & Concepts

AMPKPhosphorylationLife spanSpan (engineering)Cell biologyComputer scienceBiologyProtein kinase AEvolutionary biologyEngineeringStructural engineeringNuclear Structure and FunctionRNA Research and SplicingMuscle Physiology and Disorders