CXCR4 induces cell autophagy and maintains EBV latent infection in EBVaGC
Weiwen Wang, Yan Zhang, Wen Liu, Xiangyan Zhang, Hua Xiao, Menghe Zhao, Bing Luo
Abstract
Our data suggested new roles for CXCR4 in autophagy and EBV replication in EBVaGC, which further promoted cell survival and persistent latent infection. These new findings can lead to further CXCR4-based anticancer therapy.
Topics & Concepts
AutophagyCXCR4VirologyCell biologyCellBiologyCancer researchImmunologyChemokineImmune systemBiochemistryApoptosisViral-associated cancers and disordersCytomegalovirus and herpesvirus researchParvovirus B19 Infection Studies