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Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features

Carolina Oliveira Costa Fechine, Neusa Yuriko Sakai Valente, Ricardo Romiti

2022Anais Brasileiros de Dermatologia68 citationsDOIOpen Access PDF

Abstract

Lichen planopilaris and frontal fibrosing alopecia are primary scarring alopecias where diagnosis can be suggested by clinical and trichoscopy features, especially in the early stages, but scalp biopsy is the standard exam for definitive diagnosis. Frontal fibrosing alopecia is considered a variant of lichen planopilaris, as the histopathological findings are similar, with a perifollicular lymphohistiocytic infiltrate, sometimes with a lichenoid pattern. A thorough clinical examination, trichoscopy and photographic documentation are essential to assess the evolution and therapeutic response. To date, there are no validated treatments or guidelines for these diseases, but there are recommendations that vary with the individual characteristics of each patient. This article presents a comprehensive review of the literature, including an update on topics related to the diagnosis, follow-up, histopathological aspects and available treatments for lichen planopilaris and frontal fibrosing alopecia, highlighting their similarities, differences and peculiarities.

Topics & Concepts

Scarring alopeciaMedicineDermatologyScalpPathologyBiopsyHair Growth and DisordersSkin and Cellular Biology ResearchGenetic and rare skin diseases.
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