Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides
Cem Yamalı, Halise İnci Gül, Gulsen Ozli, Andrea Angeli, Petek Ballar, Burcu Erbaykent Tepedelen, Hiroshi Sakagami, Silvia Bua, Claudiu T. Supuran
Topics & Concepts
ChemistryCytotoxicityPyrazoleCancer researchCell cultureApoptosisCell cycleCytotoxic T cellIsozymeCellCarbonic anhydraseIn vitroBiochemistryMolecular biologyPharmacologyEnzymeStereochemistryBiologyGeneticsEnzyme function and inhibitionSynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and Activities