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Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin

Jie Yang, Hasenbilige, Shibo Bao, Shengxiang Luo, Liping Jiang, Qiujuan Li, Ying Kong, Jun Cao

2023Food and Chemical Toxicology13 citationsDOI

Topics & Concepts

CurcuminAutophagyPI3K/AKT/mTOR pathwayProtein kinase BChemistryA549 cellUnfolded protein responseCell biologyCancer researchApoptosisBiologyBiochemistryAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseLipid metabolism and biosynthesis
Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin | Litcius