Protection of DNA by metal ions at 95 °C: from lower critical solution temperature (LCST) behavior to coordination-driven self-assembly
Chang Lu, Yuancong Xu, Po‐Jung Jimmy Huang, Mohamad Zandieh, Yihao Wang, Jinkai Zheng, Juewen Liu
Abstract
concentration. The unexpected thermal stability of DNA enabled by metal ions is useful for extending the application of DNA at high temperatures, forming coordination-driven nanomaterials, and it might offer insights into the origin of life on the early Earth.
Topics & Concepts
Lower critical solution temperatureIonMetal ions in aqueous solutionMaterials scienceMetalSelf-assemblyNanotechnologyChemical engineeringChemistryPolymerOrganic chemistryMetallurgyEngineeringCopolymerComposite materialAdvanced biosensing and bioanalysis techniquesMolecular Sensors and Ion DetectionDNA and Nucleic Acid Chemistry