Selective Electrochemical Synthesis of 9-Aryl-10-sulfonyl Substituted Phenanthrene from Alkynes and Sulfonyl Hydrazides
Haodong Tian, Zihao Fu, Chen Li, Huang-Chu Lin, Ming Li, Shao‐Fei Ni, Li‐Rong Wen, Lin‐Bao Zhang
Abstract
An efficient electrochemical synthesis of sulfonated phenanthrenes via the reaction of internal alkynes with sulfonyl hydrazides has been established. The protocol does not require a metal catalyst or external oxidants, providing a green and mild route to functionalized phenanthrenes. Moreover, the compatibility of various functional groups and decagram-scale experimental conditions demonstrate the practicality of the electrochemical strategy.
Topics & Concepts
SulfonylChemistryPhenanthrenesArylElectrochemistryCatalysisPhenanthreneCombinatorial chemistryOrganic chemistryPhysical chemistryElectrodeAlkylSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods