Malignant melanotic nerve sheath tumor with PRKAR1A, KMT2C and GNAQ mutations
Merryl Terry, Kristina Wakeman, Brian J. Williams, Donald M. Miller, Müge Sak, Zied Abdullaev, M. Cristina Pacheco, Kenneth Aldape, Norman L. Lehman
Abstract
mutations are not always mutually exclusive and that neither can be used to differentiate MMNST or MPNST from all melanocytic lesions.
Topics & Concepts
GNAQMelanomaMalignant peripheral nerve sheath tumorCarney complexLesionMedicinePathologyCancer researchBiologyMutationImmunohistochemistryGeneticsGeneNeurofibromatosis and Schwannoma CasesGlioma Diagnosis and TreatmentMeningioma and schwannoma management