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Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab

Jian Sun, Xiangxiang Zhang, Xue Liu, Liang Cheng, Jing Zhang, Xin Chen, Zhirong Shen, Kang Li, Lai Wang, Chichi Huang, Jing Song

2024Structure10 citationsDOIOpen Access PDF

Topics & Concepts

TIGITChemistryAntibodyMonoclonal antibodyBinding siteLigand (biochemistry)Cancer researchCell biologyMolecular biologyReceptorBiochemistryBiologyImmunologyIn vitroCytotoxic T cellImmune Cell Function and InteractionMonoclonal and Polyclonal Antibodies ResearchCAR-T cell therapy research
Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab | Litcius