Litcius/Paper detail

Applications of the DIB–BBr<sub>3</sub> Protocol in Bromination Reactions

Liangkun Pan, Ka-Mei Lee, Yung‐Yin Chan, Zhihai Ke, Ying‐Yeung Yeung

2023Organic Letters12 citationsDOI

Abstract

Non-symmetrical bromoiodanes are useful for bromination reactions, and some protocols were found to be suitable for specific substrates. Herein, we report the use of a DIB/BBr 3 protocol for various bromination reactions, including electrophilic bromination of arenes, carbonyl C–H monobromination, bromolactonization, bromocarbocyclization, intermolecular bromoetherification of olefin, and light-triggered C(sp 3 )–H bromination.

Topics & Concepts

HalogenationChemistryElectrophileOlefin fiberIntermolecular forceMedicinal chemistryOrganic chemistryMoleculeCatalysisOxidative Organic Chemistry ReactionsVanadium and Halogenation ChemistryCatalysis and Oxidation Reactions